Three-Phase Partitioning for the Extraction and Purification of Polysaccharides from the Immunomodulatory Medicinal Mushroom Inonotus obliquus
نویسندگان
چکیده
منابع مشابه
Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus
The immunomodulatory effect of aqueous extract of Inonotus obliquus, called as Chaga, was tested on bone marrow cells from chemically immunosuppressed mice. The Chaga water extract was daily administered for 24 days to mice that had been treated with cyclophosphamide (400 mg/kg body weight), immunosuppressive alkylating agent. The number of colony-forming unit (CFU)-granulocytes/macrophages (GM...
متن کاملNew antioxidant polyphenols from the medicinal mushroom Inonotus obliquus.
The fruiting body of Inonotus obliquus, a medicinal mushroom called chaga, has been used as a traditional medicine for cancer treatment. Although this mushroom has been known to exhibit potent antioxidant activity, the mechanisms responsible for this activity remain unknown. In our investigation for free radical scavengers from the methanolic extract of this mushroom, inonoblins A (1), B (2), a...
متن کاملProgress on understanding the anticancer mechanisms of medicinal mushroom: inonotus obliquus.
Cancer is a leading cause of death worldwide. Recently, the demand for more effective and safer therapeutic agents for the chemoprevention of human cancer has increased. As a white rot fungus, Inonotus obliquus is valued as an edible and medicinal resource. Chemical investigations have shown that I. obliquus produces a diverse range of secondary metabolites, including phenolic compounds, melani...
متن کاملOptimization of Subcritical Water Extraction of Polysaccharides from Inonotus Obliquus and their Antioxidant Activities
Subcritical water extraction (SWE) of Inonotus Obliquus polysaccharides (IOP) was investigated using response surface methodology (RSM) with a design by Box–Behnken design (BBD). Results showed that the optimum SWE conditions for IOP production were as follows: extraction temperature 194°C, residence time 5.36 min and liquidsolid ratio 53 mL/g, yielding 168.80 ± 0.59 mg/g of IOP, which was in c...
متن کاملAntioxidative Properties of Crude Polysaccharides from Inonotus obliquus
The mushroom Inonotus obliquus has been widely used as a folk medicine in Russia, Poland and most of the Baltic countries. In this study, water-soluble and alkali-soluble crude polysaccharides (IOW and IOA) were isolated from I. obliquus, and the carbohydrate-rich fractions IOW-1 and IOA-1 were obtained respectively after deproteination and depigmentation. Their contents, such as neutral carboh...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2019
ISSN: 1420-3049
DOI: 10.3390/molecules24030403